Dexrazoxane Intermediate
| Item | Standards |
|---|---|
| Appearance | Off white to yellowish crystalline powder |
| Water Content | Not more than 5% |
| Specific Optical Rotation (4% w/v solution in water at 25℃) | Between -4.0° to -6.0° |
| Purity by GC | Not less than 99% |
| Assay by Titrimetry (on anhydrous basis) | Not less than 98% |
| Enantiomeric Ppurity by HPLC R-Enantiomer | Not more than 0.1% |
Description:
Dexrazoxane (DEX) CAS No. 24584-09-6, a cytoprotective agent, is a chiral drug first synthesized by Creighton in 1976 and has been successfully used to prevent or reduce the cardiotoxicity of doxorubicin. (S)-(-)-propylenediamine dihydrochloride CAS No. 19777-66-3 is a Dexrazoxane precursor. 1,2-propanediamine dihydrochloride is resoluted from 1,2-Diaminopropane CAS No. 78-90-0 using D(-)-Tartaric acid CAS No. 147-71-7.
Application:
(S)-(-)-propylenediamine dihydrochloride CAS No. 19777-66-3 can be used as Dexrazoxane precursor, Dexrazoxane intermediate, Pharmaceutical intermediate.
(S)-(-)-propylenediamine dihydrochloride Cas No: 19777-66-3
(S)-(-)-propylenediamine dihydrochloride manufactory
(S)-(-)-propylenediamine dihydrochloride manufactory of China
A: 1KG
Q: How to Get Sample of (S)-(-)-propylenediamine dihydrochloride?
A: Sample within 500g could be sent for free once buyer’s DHL account is advised for freight collect or courier cost is paid. The courier cost could be deducted when bulk order is placed.
Q: What is Lead Time of Cas No: 19777-66-3 ?
A: Generally, cargo could be loaded on ship in about two weeks after the date of receiving prepayment or L/C. Sometimes one week earlier or later.
Q: What’s the bulk Packing of (S)-(-)-propylenediamine dihydrochloride?
A: In 5kg or 25kg drum.
Q: What is Dexrazoxane Intermediate?
A: Dexrazoxane Intermediate is a chemical compound that is used in the production of the medication dexrazoxane.
Q: What is dexrazoxane used for?
A: Dexrazoxane is used to prevent heart damage in patients who are receiving chemotherapy for certain types of cancer.
Q: How is dexrazoxane administered?
A: Dexrazoxane is administered intravenously (through a vein) by a healthcare provider.
Q: What are the benefits of using dexrazoxane?
A: Dexrazoxane can help prevent damage to the heart muscle caused by certain chemotherapy drugs, which can improve a patient’s overall quality of life.
Q: Are there any side effects associated with dexrazoxane?
A: Like all medications, dexrazoxane can cause side effects. Common side effects include nausea, vomiting, and low blood pressure.
Q: Can dexrazoxane be used in all patients receiving chemotherapy?
A: No, dexrazoxane is only recommended for patients who are receiving certain types of chemotherapy that are known to cause heart damage.
Q: Is dexrazoxane safe for use during pregnancy or breastfeeding?
A: The safety of dexrazoxane during pregnancy or breastfeeding has not been established. Women who are pregnant or breastfeeding should consult with their healthcare provider before receiving dexrazoxane.
